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Amuvatinib hydrochloride
CAS No. : 1055986-67-8
Biological Activity：Amuvatinib hydrochloride (MP470 hydrochloride) is an orally bioavailable multi-targeted tyrosine kinase inhibitor with potent activity against mutant c-Kit, PDGFRα, Flt3, c-Met and c-Ret. Amuvatinib hydrochloride (MP470 hydrochloride) is also a DNA repair suppressor through suppression of DNA repair protein RAD51, thereby disrupting DNA damage repair[2][3]. Antineoplastic activity[4].
Research Area：Cancer
Targets：FLT3|RAD51|c-Met/HGFR|RET|c-Kit|PDGFR
Related Small Molecules:AMG-208;D6808;AT9283;(E/Z)-Zotiraciclib;MET kinase-IN-2;Henatinib;c-Met-IN-9;Crotonoside;Tyrosine kinase-IN-4;c-Kit-IN-5-1;Flumatinib mesylate;IHMT-TRK-284;FLT3-IN-13;RET-IN-18;PDGFRα/FLT3-ITD-IN-2;FLT3/CDK4-IN-1;Savolitinib;PP58;Chiauranib;Foretinib;Zeteletinib;RI-1;HP1142;RAD51-IN-6;Pexidartinib
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