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ABBV-744
CAS No. : 2138861-99-9
Biological Activity：ABBV-744 is a first-in-class, orally active and selective inhibitor of the BDII domain of BET family proteins with IC50 values ranging from 4 to 18 nM for BRD2, BRD3, BRD4 and BRDT. ABBV-744 is primarily metabolized by CYP3A4 with drug-like properties enable the investigation of its antitumor efficacy and tolerability.
Research Area：Cancer|Infection|Inflammation/Immunology
Targets：Epigenetic Reader Domain|HIV
Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound Library Plus;Anti-Infection Compound Library;Epigenetics Compound Library;Immunology/Inflammation Compound Library;Histone Modification Research Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Antiviral Compound Library;Reprogramming Compound Library;Orally Active Compound Library;Chemical Probe Library; Anti-Blood Cancer Compound Library;
Related Small Molecules:RVX-297;BRD4 Inhibitor-19;HIV-1 TAT (48-60);Seletracetam lithium;HIV-IN-2;UNC6349 (Ket2);Curcumin;Triptonine B;GSK6853;GSK4028;FC131;Peritassine A;SR-0813;Flavopiridol;Inobrodib;TAT (48-57);FGI-106 tetrahydrochloride;(Z)-9-Propenyladenine;Apabetalone;OF-1;I-CBP112;Decanoyl-RVKR-CMK TFA;ONX-0914 TFA
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
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