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CAS No. : 1365267-27-1

Biological Activity:X-376 is a potent and highly specific ALK tyrosine kinase inhibitor (TKI) (IC50=0.61 nM). X-376 is a less potent inhibitor of MET (IC50=0.69 nM). X-376 displays potent anti-tumor activity.

Research Area:Cancer

Targets:c-Met/HGFR|Anaplastic lymphoma kinase (ALK)

Related Screening Libraries:Bioactive Compound Library Plus;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;Anti-Cancer Compound Library;Anti-Lung Cancer Compound Library;Anti-Blood Cancer Compound Library;Angiogenesis-Related Compound Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Cancer Stem Cells Compound Library;

Related Small Molecules:AMG-208;ALK-IN-9;D6808;MET kinase-IN-2;c-Met-IN-9;Tyrosine kinase-IN-4;KRCA-0008;Savolitinib;Foretinib;Alectinib-d8;PF-04217903 phenolsulfonate;MS4078;MK-2461;TL13-22;XL092;SAR125844;MK-8033 hydrochloride;NVP-TAE 684;ALK5-IN-30;TL13-112;ALK-IN-22;BPI-9016M;Ficlatuzumab;Alectinib;ALK-IN-12;Meleagrin;Entrectinib

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