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Talarozole
CAS No. : 201410-53-9
Biological Activity：Talarozole (R115866) is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA) which increases intracellular levels of endogenous all-trans retinoic acid (RA). Talarozole inhibits both CYP26A1 and CYP26B1 with IC50s of 5.4 and 0.46 nM, respectively.
Research Area：Inflammation/Immunology
Targets：Autophagy|RAR/RXR|Cytochrome P450
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Metabolism/Protease Compound Library;Clinical Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Antioxidant Compound Library;Oxygen Sensing Compound Library;Transcription Factor-Targeted Library;Protein-protein Interaction Inhibitor Library;Human Metabolite Library;Nuclear Receptor Compound Library;Non-steroidal Anti-Inflammatory Compound Library;
Related Small Molecules:SR9186;AMG-208;AGN 193109-d7;CYP1B1-IN-1;CYP2C9/CYP2C19-IN-1;Hypericin;Retinoic acid;Galeterone;Ranitidine;Bergapten;Ginsenoside Rd;AS1810722;Isoglycycoumarin;Polygalaxanthone III;Phenyltoloxamine;Ezutromid;Seviteronel;β-Apo-8′-carotenal;Diosmetin-d3;EDP-305;Fipronil
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