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SR-318
CAS No. : 2413286-32-3
Biological Activity：SR-318 is a potent and highly selective p38 MAPK inhibitor with IC50s of 5 nM, 32 nM and 6.11 μM for p38α, p38β and p38α/β, respectively. SR-318 potently inhibits the TNF-α release in whole blood with an IC50 of 283 nM. SR-318 has anti-cancer and anti-inflammatory activity.
Research Area：Cancer|Inflammation/Immunology
Targets：TNF Receptor|p38 MAPK
Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;MAPK Compound Library;Anti-Cancer Compound Library;Differentiation Inducing Compound Library;Reprogramming Compound Library;Oxygen Sensing Compound Library;Pyroptosis Compound Library;Chemical Probe Library;Anti-Lung Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Neurodegenerative Disease-related Compound Library;Anti-Obesity Compound Library;Angiogenesis-Related Compound Library;Antidepressant Compound Library;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:Akt/NF-κB/JNK-IN-1;AX-024;SB-747651A dihydrochloride;Dehydrocorydaline;SKF-86002 dihydrochloride;QNZ;Sinulatumolin E;Pexmetinib;Epobis;SB 242235;Mulberroside A;Sinulatumolin D;TA-01;PDE4-IN-10;Ginsenoside Rc;TIC10;Anti-inflammatory agent 7;MW-150;Teneliximab;VX-702;Loganic acid 6′-O-β-D-glucoside;R1487 Hydrochloride;VGX-1027;D-Trimannuronic acid;DCVC;MBP MAPK Substrate;Gamma-glutamylcysteine TFA
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