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Repotrectinib

CAS No. : 1802220-02-5

Biological Activity：Repotrectinib (TPX-0005) is a potent ROS1 (IC₅₀=0.07 nM) and TRK (IC₅₀=0.83/0.05/0.1 nM for TRKA/B/C) inhibitor. Repotrectinib potently inhibits WT ALK (IC₅₀=1.01 nM). Repotrectinib has anti-cancer activity^[2].

Research Area：Cancer

Targets：Trk Receptor|ROS Kinase|Anaplastic lymphoma kinase (ALK)

Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Kinase Inhibitor Library;Neuronal Signaling Compound Library;Protein Tyrosine Kinase Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Drug Repurposing Compound Library;Macrocyclic Compound Library;Anti-COVID-19 Compound Library;Orally Active Compound Library;Anti-Lung Cancer Compound Library;

Related Small Molecules:ALK-IN-9;hTrkA-IN-1;IHMT-TRK-284;KRCA-0008;ANA-12;Alectinib-d8;Taletrectinib;Larotrectinib sulfate;N-Acetyl-5-hydroxytryptamine;MS4078;LM22B-10;TL13-22;D5261;NVP-TAE 684;N-Acetyl-5-hydroxytryptamine-d3;GGTI-2154 hydrochloride;MitoPQ;7,8-Dihydroxyflavone;TRK-IN-18;ALK5-IN-30;TL13-112;TRK-IN-12;ALK-IN-22;Alectinib;ALK-IN-12;CH7057288;Entrectinib;ALK kinase inhibitor-1;Pan-Trk-IN-3

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