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Protosappanin A
CAS No. : 102036-28-2
Biological Activity：Protosappanin A (PTA), an immunosuppressive ingredient and major biphenyl compound isolated from Caesalpinia sappan L, suppresses JAK2/STAT3-dependent inflammation pathway through down-regulating the phosphorylation of JAK2 and STAT3.
Research Area：Inflammation/Immunology
Targets：JAK|STAT
Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Epigenetics Compound Library;Immunology/Inflammation Compound Library;JAK/STAT Compound Library;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;Stem Cell Signaling Compound Library;Natural Product Library;Small Molecule Immuno-Oncology Compound Library;Anti-Aging Compound Library;Phenols Library;Pyroptosis Compound Library;Traditional Chinese Medicine Active Compound Library;Anti-Lung Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Transcription Factor-Targeted Library;Anti-inflammatory Traditional Chinese Medicine Active Compound Library;Plant-Sourced Natural Product Library;Human Metabolite Library;
Related Small Molecules:AZ-3;JAK3/BTK-IN-1;Cirsilineol;Ochromycinone;AT9283;C188-9;Benzene hexabromide;STAT3-IN-10;(E/Z)-Zotiraciclib;JAK-IN-10;C188;Baricitinib-d3;JAK3-IN-6;Niclosamide monohydrate;STAT3-IN-1;STAT3 degrader-1;Coumermycin A1;Deucravacitinib;Momelotinib-3,3,5,5-d4;PM-81I;SJ10542;Delgocitinib;Morusin;Nifuroxazide-13C6;AS1810722;Upadacitinib;α7 nAchR-JAK2-STAT3 agonist 1
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