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MSC1094308
CAS No. : 2219320-08-6
Biological Activity:MSC1094308 is a non-competitive and reversible VPS4B/p97 (VCP) (I/II type AAA ATPase) allosteric inhibitor, with IC50 values of 0.71 μM and 7.2 μM for VPS4B and p97, respectively. MSC1094308 inhibits the D2 ATPase activity by binding to a drugable hotspot of p97. MSC1094308 can be used in study of cancer.
Research Area:Cancer
Targets:p97
Related Screening Libraries:Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Anti-Cancer Compound Library;Antiviral Compound Library;Anti-Aging Compound Library;Ubiquitination Compound Library;Endoplasmic Reticulum Stress Compound Library;Exosomes Compound Library;
Related Small Molecules:DBeQ;NMS-859;NMS-873;UPCDC-30245;ML240;VCP/p97 inhibitor-1;CB-5339;CB-5083;ML241 hydrochloride;Eeyarestatin I;NW 1028
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