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MRT00033659
CAS No. : 1401731-54-1
Biological Activity：MRT00033659 is a potent broad-spectrum kinase inhibitor of CK1 (IC50=0.9 µM for CK1δ) and CHK1 (IC50=0.23 µM). MRT00033659, a pyrazolo-pyridine analogue, induces p53 pathway activation and E2F-1 destabilisation.
Research Area：Cancer
Targets：Casein Kinase|MDM-2/p53|Checkpoint Kinase (Chk)|Early 2 Factor (E2F)
Related Screening Libraries:Bioactive Compound Library Plus;
Related Small Molecules:Umbralisib hydrochloride;MDM2-p53-IN-15;MC-VC-PABC-SP 141;p53 and MDM2 proteins-interaction-inhibitor (racemic);Navtemadlin;VER-00158411;MD-224;4,5,6,7-Tetrabromo-1H-benzimidazole;Mutant p53 modulator-1;MDM2/4-p53-IN-2;MX69;p-nitro-Pifithrin-α;RG7112;MMRi62;TA-01;BML-277;Ellagic acid;CHK1-IN-3;Anticancer agent 50;NSC59984;CK2 inhibitor 3;Pifithrin-β hydrobromide;Ivaltinostat formic;GEM-5;TMCB;Tenovin-6;GDC-0425;PK11007
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