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Merestinib
CAS No. : 1206799-15-6
Biological Activity：Merestinib (LY2801653) is a potent, orally bioavailable c-Met inhibitor (Ki=2 nM) with anti-tumor activities. Merestinib (LY2801653) also has potent activity against MST1R (IC50=11 nM), FLT3 (IC50=7 nM), AXL (IC50=2 nM), MERTK (IC50=10 nM), TEK (IC50=63 nM), ROS1, DDR1/2 (IC50=0.1/7 nM) and MKNK1/2 (IC50=7 nM)[2].
Research Area：Cancer
Targets：Discoidin Domain Receptor|FLT3|c-Met/HGFR|ROS Kinase
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Drug Repurposing Compound Library;Orally Active Compound Library;Anti-Lung Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Angiogenesis-Related Compound Library;Anti-Liver Cancer Compound Library ;Rare Diseases Drug Library;Anti-Colorectal Cancer Compound Library ;Anti-Prostate Cancer Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:JNK3 inhibitor-2;AMG-208;D6808;AT9283;(E/Z)-Zotiraciclib;MET kinase-IN-2;c-Met-IN-9;Crotonoside;Tyrosine kinase-IN-4;FLT3-IN-13;PDGFRα/FLT3-ITD-IN-2;FLT3/CDK4-IN-1;Savolitinib;Foretinib;HP1142;PF-04217903 phenolsulfonate;ENMD-2076 Tartrate;Taletrectinib;ATH686;AZD2932;DDR2-IN-1;MK-2461;AKN-028 acetate;XL092;FLT3-IN-3;SAR125844;UNC2025 hydrochloride;DDR1-IN-1 dihydrochloride;MK-8033 hydrochloride
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