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CAS No. : 1435265-06-7

Biological Activity:HCH6-1 is a potent and competitive dipeptide antagonist of Formyl peptide receptor 1 (FPR1). HCH6-1 inhibits chemotaxis, superoxide anion generation, and elastase release in human neutrophils specifically activated by fMLF (an FPR1 agonist). HCH6-1 has protective effects against acute lung injury (ALI) in vivo and can be used for the research of FPR1-involved inflammatory lung diseases.

Research Area:Inflammation/Immunology

Targets:Formyl Peptide Receptor (FPR)

Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Immunology/Inflammation Compound Library;Targeted Diversity Library;

Related Small Molecules:WKYMVM;BMS-986235;WRW4 TFA;FPR Agonist 43;{Boc}-Phe-Leu-Phe-Leu-Phe TFA;ACT-389949;N-Formyl-Met-Leu-Phe-Lys;Ac9-25;Boc-MLF TFA;N-Boc-Phe-Leu-Phe-Leu-Phe;WKYMVM-NH2 TFA;N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys;Cyclosporin H;AG-09/1

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