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CAS No. : 1426802-50-7

Biological Activity:GSK805 is an orally active and CNS penetrant RORγt inhibitor. GSK805 inhibits RORγ and Th17 cells differentiation with pIC50 values of 8.4 and >8.2. GSK805 inhibits the function of Th17 cells. GSK805 can be used for the research of immunity.

Research Area:Inflammation/Immunology


Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Metabolism/Protease Compound Library;CNS-Penetrant Compound Library;Small Molecule Immuno-Oncology Compound Library;Orally Active Compound Library;Transcription Factor-Targeted Library;Nuclear Receptor Compound Library;

Related Small Molecules:RORγt inhibitor 1;GNE-6468;SR3335;RORγt inverse agonist 30;GNE-0946;RORγt inverse agonist 13;Vimirogant hydrochloride;SR2211;Bevurogant;ROR agonist-1;RORγt Inverse agonist 8;CD12681;S18-000003;RORγt inhibitor 2;XY018;RORγt inverse agonist 29;SR1001;Cedirogant;SHR168442;ARN-6039;A-9758;Cintirorgon;Nobiletin;TAK-828F;RORγt inverse agonist 26;PF-06747711;Zilovertamab;(±)-ML 209

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