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CVT-10216

CAS No. : 1005334-57-5

Biological Activity：CVT-10216 is a highly selective, reversible aldehyde dehydrogenase-2 (ALDH-2) inhibitor with an IC₅₀ of 29 nM. CVT-10216 also has inhibitory effect of ALDH-1 with an IC₅₀ of 1.3 μM. CVT-10216 can reduce excessive alcohol drinking in alcohol-preferring rats and exhibit anxiolytic effects.

Research Area：Neurological Disease

Targets：Aldehyde Dehydrogenase (ALDH)

Related Screening Libraries:Natural Product-like Compound Library;Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Glutamine Metabolism Compound Library;Anti-Cancer Metabolism Compound Library;Targeted Diversity Library;Cancer Stem Cells Compound Library;

Related Small Molecules:Alda-1;ALDH3A1-IN-2;NCT-501 hydrochloride;ALDH1A3-IN-2;CM10;EN40;Prunetin;ALDH1A1-IN-3;Taraxerone;Win 18446;RV01;KS100;CM037;IGUANA-1 free base;4-Diethylaminobenzaldehyde;KS106;α-NETA;ALDH1A2-IN-1;CM121;ALDH1A3-IN-1;3-Hydroxybenzaldehyde;ALDH3A1-IN-1;NCT-505;4-Hydroxynonenal-d3;NCT-506;ALDH1A3-IN-3;Dyclonine hydrochloride

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