Aurora A/PKC-IN-1

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Aurora A/PKC-IN-1

CAS No. : 2143100-98-3

Biological Activity:Aurora A/PKC-IN-1 (Compound 2e) is a potent dual inhibitor of Aurora A (AurA) and PKC (α, β1, β2, and θ) kinases with IC50s of 6.9 nM and 16.9 nM for AurA and PKCα, respectively. Aurora A/PKC-IN-1 has antiproliferative activity in breast cancer cells and antimetastatic activity.

Research Area:Cancer

Targets:PKC|Aurora Kinase

Related Small Molecules:DB0614;[Ala107]MBP(104-118) TFA;BJE6-106;Myelin Basic Protein;AT9283;Staurosporine;PKC-iota inhibitor 1;Hypericin;Malantide;PKCiota-IN-2 formic;Chiauranib;ENMD-2076 Tartrate;PF-4950834;C8 Dihydroceramide;Barasertib-HQPA;SC-9;AMG 900;SCH-1473759;DL-erythro-Dihydrosphingosine;Safingol;BI-847325;ZIP;Psychosine-d5;TPPB

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