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α-Lipoic Acid sodium
CAS No. : 2319-84-8
Biological Activity：α-Lipoic Acid (Thioctic acid) sodium is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid sodium inhibits NF-κB-dependent HIV-1 LTR activation[2][3]. α-Lipoic Acid sodium induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells[4]. α-Lipoic Acid sodium can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1[5].
Research Area：Cancer|Infection|Inflammation/Immunology
Targets：NF-κB|HIV|Endogenous Metabolite|Apoptosis|Mitochondrial Metabolism
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