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Yhhu-3792
CAS No. : 2097826-24-7
Biological Activity：Yhhu-3792 enhances the self-renewal capability of neural stem cells (NSCs). Yhhu-3792 activates Notch signaling pathway and promotes the expression of Hes3 and Hes5. Yhhu-3792 expands the NSCs pool and promotes endogenous neurogenesis in the hippocampal dentate gyrus (DG) in mouse. Yhhu-3792 increases the spatial and episodic memory abilities of mice. Yhhu-3792 has the potential for the research of impairment of learning and memory associated DG dysfunction.
Research Area：Neurological Disease
Targets：Notch
Related Screening Libraries:Bioactive Compound Library Plus;Neuronal Signaling Compound Library;Stem Cell Signaling Compound Library;Wnt/Hedgehog/Notch Compound Library;Anti-Aging Compound Library;Anti-Pancreatic Cancer Compound Library;Angiogenesis-Related Compound Library;Transcription Factor-Targeted Library;Osteogenesis Compound Library;
Related Small Molecules:ZLDI-8;Crenigacestat;FLI-06;JI051;Demcizumab;Notch inhibitor 1;Tarextumab;Notch 1 TFA;Bruceine D;Psoralidin;YO-01027 (GMP);Brontictuzumab;Semagacestat;BMS-983970;SAHM1 TFA;LY-411575;CB-103;Jagged-1 (188-204) (TFA);Tangeretin;Z-Ile-Leu-aldehyde;tCFA15
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