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WX-081
CAS No. : 1859978-72-5
Biological Activity:WX-081, an anti-tuberculosis agent, displays excellent anti-mycobacterial activity against M. tuberculosis H37Rv and low cytotoxicity. WX-081 exhibits potent activity with MIC50s of 0.083 and 0.11 μg/mL for drug susceptible tuberculosis (DS-TB) and multidrug resistant tuberculosis (MDR-TB) strains. WX-081 also inhibits hERG channel with the IC50 of 1.89 μM.
Research Area:Infection
Targets:Potassium Channel|Bacterial|Antibiotic
Related Small Molecules:Sandramycin;LLO (91-99);Gepotidacin;Oritavancin;Monascorubrin;Azlocillin sodium salt;Herbimycin A;Antibacterial agent 45;Leucomycin;Isouvaretin;Antibacterial agent 99;Vidarabine monohydrate;Nafcillin;Antitubercular agent-28;Ochromycinone;Staurosporine;Nucleocidin;Kv3 modulator 2;(±)-Leucine-13C-1;Ciclopirox-d11;Ciclopirox olamine;Clotrimazole-d5;SQ109
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