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Type II topoisomerase inhibitor 1
CAS No. : 2245691-60-3
Biological Activity：Type II topoisomerase inhibitor 1 is a potent and selective E. coli DNA gyrase inhibitor (IC50: 1.7 nM), and forms hydrogen bonds with Asp73 residue. Type II topoisomerase inhibitor 1 inhibits topoisomerase IV activity (IC50: 0.98 μM). Type II topoisomerase inhibitor 1 can be used in the research of antibacterial area[2].
Research Area：Infection
Targets：Topoisomerase|DNA/RNA Synthesis|Bacterial
Related Small Molecules:Sandramycin;LLO (91-99);Gepotidacin;Oritavancin;Azlocillin sodium salt;Herbimycin A;Antibacterial agent 45;Leucomycin;Ametantrone;Isouvaretin;ddCTP trisodium;7-TFA-ap-7-Deaza-dA;Antibacterial agent 99;Nafcillin;Antitubercular agent-28;Ochromycinone;Staurosporine;Topoisomerase I/II inhibitor 3;Nucleocidin;(±)-Leucine-13C-1;Ciclopirox-d11;Ciclopirox olamine;Clotrimazole-d5
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