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TC11
CAS No. : 100823-03-8
Biological Activity:TC11 is a MCL1 degrader. TC11 is also a Caspase-9 and CDK1 activator. TC11 structurally relates to immunomodulatory drugs as phenylphthalimide derivative. TC11 induces apoptotic death caused by degradation of MCL1 during prolonged mitotic arrest[2].
Research Area:Cancer
Targets:CDK|Bcl-2 Family|Caspase
Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Cell Cycle/DNA Damage Compound Library;Kinase Inhibitor Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Anti-Breast Cancer Compound Library;Anti-Blood Cancer Compound Library;Targeted Diversity Library;
Related Small Molecules:DB0614;Dinaciclib;SNS-032;CC-671;BI-3812;(E/Z)-Zotiraciclib;Pyridoclax;CDK1-IN-4;PUMA BH3 TFA;CCT-251921;Dehydrocorydaline;BS-181;Samuraciclib hydrochloride hydrate;T025;Flavopiridol;CDK8-IN-3;CDK9-IN-12;FLT3/CDK4-IN-1;GFB-12811;GSK 3 Inhibitor IX;Z-DEVD-AMC;Eciruciclib;CDK-IN-6;Bufarenogin;Murizatoclax;Lerociclib dihydrochloride;CDK4/6-IN-13;ON-013100
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