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p,p’-DDE
CAS No. : 72-55-9
Biological Activity:p,p’-DDE (4,4′-DDE), a major metabolite of persistent dichlorodiphenyltrichloroethane (DDT), is a potent androgen receptor antagonist, with an IC50 of 5 μM and a Ki of 3.5 μM.
Research Area:Endocrinology
Targets:Drug Metabolite|Androgen Receptor
Related Screening Libraries:Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Endocrinology Compound Library;Transcription Factor-Targeted Library;Drug Metabolite Library;Tumorigenesis-Related Compound Library;Human Metabolite Library;Anti-Prostate Cancer Compound Library;Nuclear Receptor Compound Library;
Related Small Molecules:Nicotinamide N-oxide;VPC-14449;4-Hydroxyphenylbutazone;Ampyrone;Resveratrol-3-O-sulfate sodium;AC-262536;Sonidegib metabolite M48;Isonicotinic acid;Cycloguanil hydrochloride;Hydroxytanshinone IIA;GTx-007;Endoxifen;Linuron-d6;MI-136;Fodipir;Regorafénib N-oxyde (M2)-13C,d3;AZ7550 Mesylate;AR-13324 M1 metabolite;Thyroxine sulfate;Netupitant metabolite Monohydroxy Netupitant;VPC-13789;RD162;ARD-2585;(-)-(E)-Guggulsterone;Leukotriene D4;Desbutyl Lumefantrine;(R)-3-Hydroxy Midostaurin;RP101442
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