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NPD-1335
CAS No. : 2376326-31-5
Biological Activity:NPD1335 is a Trypanosoma brucei phosphodiesterase B1 (TbrPDEB1) inhibitor with submicromolar activities against T. brucei parasites. NPD1335 displays a greatly improved cytotoxicity profile. NPD1335 increases intracellular cAMP levels and results in the distortion of the cell cycle and cell death.
Research Area:Infection|Inflammation/Immunology
Targets:Phosphodiesterase (PDE)|Parasite
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