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Margatoxin
CAS No. : 145808-47-5
Biological Activity：Margatoxin, an alpha-KTx scorpion toxin, is a high affinity inhibitor of Kv1.3 (Kd=11.7 pM). Margatoxin inhibits the Kv1.2 (Kd=6.4 pM) and Kv1.1 (Kd=4.2 nM). Margatoxin, a 39 amino-acid-long peptide, is isolated from the venom of the scorpion Centruroides margaritatus and widely used in ion channel research[2].
Research Area：Neurological Disease
Targets：Potassium Channel
Related Small Molecules:Kv3 modulator 2;Brompheniramine-d6 maleate;Pinacidil;AMP-PNP tetralithium;IK1 inhibitor PA-6;VU590;Domiphen bromide;Mesoridazine benzenesulfonate;Tetrandrine;20(S)-Ginsenoside Rg3;(S)-(+)-Modafinic acid-d5;Ketanserin;PE 22-28;Ifenprodil tartrate;Brompheniramine maleate;L-Palmitoylcarnitine-d3 hydrochloride;Phe-Met-Arg-Phe amide trifluoroacetate;Mitiglinide;Flupirtine-d4 hydrochloride;Kaliotoxin (1-37);Tifenazoxide;Agitoxin-2 TFA
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