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Lumasiran
CAS No. : 1834610-13-7
Biological Activity:Lumasiran (ALN-G01), a siRNA product, reduces hepatic oxalate production by targeting glycolate oxidase. By silencing the gene encoding glycolate oxidase, Lumasiran depletes glycolate oxidase and thereby inhibits the synthesis of oxalate, which is the toxic metabolite that is directly associated with the clinical manifestations of Primary hyperoxaluria type 1 (PH1)[2].
Research Area:Metabolic Disease
Targets:Small Interfering RNA (siRNA)
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;Bioactive Compound Library Plus;
Related Small Molecules:SLN124;Cemdisiran;Givosiran;Manusiran;Revusiran;AB-729;Teprasiran;Fazirsiran;Fitusiran;Patisiran sodium;Inclisiran;Tivanisiran;Elebsiran;Lumasiran sodium;Zerlasiran;Vutrisiran
Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
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