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GSK-690693
CAS No. : 937174-76-0
Biological Activity:GSK-690693 is an ATP-competitive pan-Akt inhibitor with IC50s of 2 nM, 13 nM, 9 nM for Akt1, Akt2 and Akt3, respectively. GSK-690693 is also an AMPK inhibitor, affects Unc-51-like autophagy activating kinase 1 (ULK1) activity and robustly inhibits STING-dependent IRF3 activation[2][3].
Research Area:Cancer
Targets:Akt|Autophagy|AMPK
Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound Library Plus;Epigenetics Compound Library;Kinase Inhibitor Library;PI3K/Akt/mTOR Compound Library;Stem Cell Signaling Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Antioxidant Compound Library;Differentiation Inducing Compound Library;Anti-diabetic Compound Library;Oxygen Sensing Compound Library;Glycolysis Compound Library;Cytoskeleton Compound Library;Glutamine Metabolism Compound Library;Anti-Breast Cancer Compound Library;Anti-Lung Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Obesity Compound Library;Angiogenesis-Related Compound Library;Transcription Factor-Targeted Library;Lipid Metabolism Compound Library ;Glucose Metabolism Compound Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:Akt/NF-κB/JNK-IN-1;AMPK activator 4;Cyclovirobuxine D;AKTide-2T;Sennidin A;ZLN024;MS98;YLF-466D;PP2A Cancerous-IN-1;1,3-Dicaffeoylquinic acid;BAY-3827;Artemisiane E;3α-Hydroxymogrol;Artemisinin-d3;AS1949490;PI3K-IN-29;TD52 dihydrochloride;LM22B-10;AT13148;HTH-01-015;Pachymic acid;Glaucocalyxin A;PI3K/AKT-IN-2;INY-03-041;N-Oleoyl glycine;Triciribine;TMPA;CCT128930;Chromeceptin
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