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Furazolidone
CAS No. : 67-45-8
Biological Activity：Furazolidone is a nitrofuran derivative with antiprotozoal and antibacterial activity, inhibits AML1-ETO transformed cells with IC50 value of 12.7 μM.
Target: Antibacterial
Furazolidone is a novel therapeutic strategy in AML patients. Furazolidone can Inhibit the bone-marrow transformation mediated by a series of leukemia fusion proteins. Furazolidone significantly inhibits proliferation of AML cell lines. Furazolidone induces apoptosis of the AML leukemic cells treatment with Furazolidone induces differentiation of AML cell lines.
Research Area：Infection|Cancer
Targets：Parasite|Bacterial|Antibiotic|Apoptosis
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Anti-Infection Compound Library;Apoptosis Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Drug Repurposing Compound Library;Antibacterial Compound Library;Anti-COVID-19 Compound Library;NMPA-Approved Drug Library;FDA Approved & Pharmacopeial Drug Library;Antibiotics Library;Drug-Induced Liver Injury (DILI) Compound Library;Anti-Blood Cancer Compound Library;Antiparasitic Compound library;Tumorigenesis-Related Compound Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;
Related Small Molecules:Physalin A;(+)-Isopulegol;Bomedemstat ditosylate;Sandramycin;LLO (91-99);Gepotidacin;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Oritavancin;Lobetyolin;Monascorubrin;SR9186;Antileishmanial agent-2;Azlocillin sodium salt;Herbimycin A;Antibacterial agent 45;Leucomycin;Isouvaretin
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