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Edoxaban
CAS No. : 480449-70-5
Biological Activity:Edoxaban (DU-176b) is an orally active, highly potent, selective, and direct Factor Xa (FXa) inhibitor with Ki values of 0.561 and 2.98 nM for free human FXa and prothrombinase. Edoxaban exhibits more than 10,000-fold selectivity over other coagulation proteases. Edoxaban can be used in preventing thromboembolic disease research.
Research Area:Cardiovascular Disease|Cancer
Targets:Thrombin|Factor Xa
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Metabolism/Protease Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Antiviral Compound Library;Drug Repurposing Compound Library;Anti-Cardiovascular Disease Compound Library;Anti-COVID-19 Compound Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Drug-Induced Liver Injury (DILI) Compound Library;Rare Diseases Drug Library;Children’s Drug Library;EMA-Approved Drug Library;FDA-Approved Anticancer Drug Library;Non-steroidal Anti-Inflammatory Compound Library;Coagulation and Anti-coagulation Compound Library;
Related Small Molecules:Bismuth subgallate;OM-189;Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride;Thrombin Inhibitor 2;Razaxaban hydrochloride;Desethyl KBT-3022;Idraparinux sodium;Betrixaban-d6;Boc-Ile-Glu-Gly-Arg-AMC;Gabexate mesylate;TP508;Inogatran;RWJ-445167;Napsagatran hydrate;FXIa-IN-8;BAY 1217224;BMS-654457;Milvexian;Thrombin (MW 37kDa)
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