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BTX161

CAS No. : 2052301-24-1

Biological Activity：BTX161, a Thalidomide analog, is a potent CKIα degrader. BTX161 mediates degradation of CKIα better than Lenalidomide in human AML cells and activates DNA damage response (DDR) and p53, while stabilizing the p53 antagonist MDM2.

Research Area：Cancer

Targets：Casein Kinase

Related Screening Libraries:Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Kinase Inhibitor Library;Stem Cell Signaling Compound Library;Wnt/Hedgehog/Notch Compound Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Cancer Stem Cells Compound Library;

Related Small Molecules:Umbralisib hydrochloride;4,5,6,7-Tetrabromo-1H-benzimidazole;TA-01;Ellagic acid;CK2 inhibitor 3;TMCB;CK2 inhibitor 2;Longdaysin;D4476;TTP 22;Orobol;(E/Z)-GO289;FPFT-2216;Silmitasertib sodium salt;Quinalizarin;PI-828;Emodin-d4;LH846;Casein Kinase inhibitor A86;BioE-1115;TMX-4116;MRT00033659;LY294002 hydrochloride;EGFR-IN-57;TBB;CK2/ERK8-IN-1;SR-3029;Casein Kinase II Inhibitor IV Hydrochloride;Epiblastin A

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