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AZ1729

CAS No. : 2016864-46-1

Biological Activity：AZ1729 is a potent free fatty acid 2 receptor (FFA2) activator, acting as a direct allosteric agonist and as a positive allosteric modulator. AZ1729 increases the activity of the endogenously produced short chain fatty acid propionate in G_i-mediated pathways, but not at those transduced by G_q/G₁₁. AZ1729 induces inhibition of isoproterenol-induced lipolysis in mouse adipocytes. AZ1729 also can Induce migration of human neutrophils. AZ1729 can be used for researching the signaling pathways of the physiological roles of FFA2.

Research Area：Metabolic Disease

Targets：Free Fatty Acid Receptor

Related Small Molecules:GW-1100;Grifolic acid;Ginsenoside Rb2;AP5;GPR40 Activator 1;AM-1638;DC260126;TUG-770;LY2881835;FFA1 agonist-1;GPR120 Agonist 3;AS2034178 free base;GPR40 Agonist 2;BMS-986118;AMG7703;Fasiglifam;MEDICA16;AR420626;AMG 837 sodium salt;Xelaglifam;TUG-1375;GPR120 Agonist 1;GPR40 agonist 5;TUG-424;GPR120 modulator 2;LY2922470;4-CMTB

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