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PRE-084 hydrochloride
CAS No. : 75136-54-8
Biological Activity：PRE-084 hydrochloride is a highly selective σ1 receptor (S1R) agonist, with an IC50 of 44 nM. PRE-084 hydrochloride exhibits good neuroprotective effects, can improve motor function and motor neuron survival in mice. PRE-084 hydrochloride also can ameliorate myocardial ischemia-reperfusion injury in rats by activating the Akt-eNOS pathway[2][3][4].
Research Area：Neurological Disease|Cardiovascular Disease
Targets：Akt|Sigma Receptor|NO Synthase
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Related Small Molecules:Carboxy-PTIO potassium;Akt/NF-κB/JNK-IN-1;Valeriandoid F;Ciwujianoside C3;Cyclovirobuxine D;NOS-IN-3;Regaloside A;AKTide-2T;Sennidin A;Aminopicoline;MS98;trans-Isoferulic acid;PP2A Cancerous-IN-1;DETA NONOate;1,3-Dicaffeoylquinic acid;Chondroitin sulfate;BD1063 dhydrochloride;Artemisiane E;3-Bromo-7-nitroindazole;Artemisinin-d3;Phenyltoloxamine;AS1949490;PI3K-IN-29;α7 nAchR-JAK2-STAT3 agonist 1;TD52 dihydrochloride;Asperuloside;LM22B-10;E1R
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