BX795

For research use only. We do not sell to patients.

BX795

CAS No. : 702675-74-9

Biological Activity：BX795 is a potent and selective inhibitor of PDK1, with an IC50 of 6 nM. BX795 is also a potent and relatively specific inhibitor of TBK1 and IKKɛ, with an IC50 of 6 and 41 nM, respectively. BX795 blocks phosphorylation of S6K1, Akt, PKCδ, and GSK3β, and has lower selectivity over PKA, PKC, c-Kit, GSK3β etc. BX795 modulates autophagy[2][3][4].

Research Area：Cancer

Targets：Autophagy|PDK-1|IKK

Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;NF-κB Signaling Compound Library;PI3K/Akt/mTOR Compound Library;Stem Cell Signaling Compound Library;Anti-Cancer Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Differentiation Inducing Compound Library;Oxygen Sensing Compound Library;Glycolysis Compound Library;Cytoskeleton Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Obesity Compound Library;Glucose Metabolism Compound Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Anti-Prostate Cancer Compound Library;Cancer Stem Cells Compound Library;

Related Small Molecules:PS-1145;NF-κB-IN-1;Resveratrol;IKK-IN-3;LDHA/PDKs-IN-2;Anti-inflammatory agent 6;PF-184;BOT-64;Siegesbeckialide I;LY2409881;MP7;Tizoxanide;PS47;CRTh2 antagonist 3;Bay 65-1942 (R form);Polyphyllin I;IKK 16;AZD3264;Chicanine;Resveratrol-d4;IMD-0560;BX-320;GSK319347A;IKK-IN-1;(R)-PS210;Ertiprotafib

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