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Bryostatin 1
CAS No. : 83314-01-6
Biological Activity:Bryostatin 1 is a natural macrolide isolated from the bryozoan Bugula neritina and is a potent and central nervous system (CNS)-permeable PKC modulator. Bryostatin 1 binds to the isolated C1 domain of Munc13-1 and the full-length Munc13-1 protein with Kis of 8.07 nM and 0.45 nM, respectively. Bryostatin 1 has anti-cancer, anti-inflammatory, neuroprotective, anti-HIV-1 infection properties[2][3][4].
Research Area:Cancer|Infection|Inflammation/Immunology|Neurological Disease
Targets:PKC|HIV|Bacterial
Related Small Molecules:Sandramycin;LLO (91-99);Gepotidacin;[Ala107]MBP(104-118) TFA;Oritavancin;Azlocillin sodium salt;Herbimycin A;Antibacterial agent 45;Leucomycin;Isouvaretin;BJE6-106;HIV-1 TAT (48-60);Antibacterial agent 99;Nafcillin;Antitubercular agent-28;Myelin Basic Protein;Ochromycinone;Seletracetam lithium;Staurosporine
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