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SP inhibitor 1

Biological Activity：SP inhibitor 1 (compound 34) is a selective SARS-CoV-2 spike protein (SP) inhibitor with an IC₅₀ of 3.26 μM, >25 μM, >25 μM for SP, M^pro and PL^pro protein, respectively. SP inhibitor 1 is a vitro SARS-CoV-2 replication inhibitor at non-toxic concentrations (0.3250<5.98 μM). SP inhibitor 1 shows cellular antiviral activity.

Research Area：Infection

Targets：Virus Protease|SARS-CoV

Related Small Molecules:SRPIN340;ZIKV-IN-4;Aminothiazole;CYP2C9/CYP2C19-IN-1;SARS-CoV-2-IN-33;GRL-0496;Grazoprevir potassium salt;SARS-CoV-2-IN-19;Molnupiravir;SARS-CoV-2 Mpro-IN-3;L-Lysine;MM3122;Ketotifen fumarate;SARS-CoV-2-IN-16;Thapsigargin;L-Lysine-13C6,15N2,d9 dihydrochloride;INSCoV-614(1B);4E2RCat;Anti-SARS-CoV-2 Spike mAb (CR3022);GNF-2;Bemnifosbuvir hemisulfate;Kansuinine B

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