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CAS No. : 953769-46-5

Biological Activity:Sotuletinib (BLZ945) is a potent, selective and brain-penetrant CSF-1R (c-Fms) inhibitor with an IC50 of 1 nM, showing more than 1,000-fold selectivity against its closest receptor tyrosine kinase homologs.

Research Area:Cancer


Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;CNS-Penetrant Compound Library;Drug Repurposing Compound Library;Anti-COVID-19 Compound Library;Anti-Blood Cancer Compound Library;

Related Small Molecules:IHMT-TRK-284;Chiauranib;Pexidartinib;GW2580-d6;CSF1R-IN-1;BPR1R024;PF 477736;GENZ-882706(Raceme);c-Fms-IN-7;c-Fms-IN-13;Anti-Mouse GM-CSF Antibody;c-Fms-IN-6;Linifanib;c-Fms-IN-8;c-Fms-IN-9;c-Fms-IN-10;RET-IN-19;GW2580;CSF1R-IN-10;PLX647 dihydrochloride;Cabiralizumab;CSF1R-IN-3;PLX5622 hemifumarate;OSI-930;CSF1R-IN-8;Dovitinib-d8;Vimseltinib;Ki20227

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