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CAS No. : 2074607-48-8

Biological Activity:IWP-O1 is a highly potent Porcupine (Porcn) inhibitor, with an EC50 of 80 pM in L-Wnt-STF cells. IWP-O1 prevents the secretion of Wnt proteins. IWP-O1 suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells.

Research Area:Cancer


Related Screening Libraries:Bioactive Compound Library Plus;Stem Cell Signaling Compound Library;Wnt/Hedgehog/Notch Compound Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Cytoskeleton Compound Library;Neuroprotective Compound Library;Anti-Breast Cancer Compound Library;

Related Small Molecules:Wnt/β-catenin agonist 1;ARUK3001185;Gallocyanine chloride;Fz7-21;LGK974;Foxy-5 TFA;Wnt/β-catenin agonist 4;JW74;IQ 1;Heparan Sulfate;ETC-159;Laduviglusib (GMP);KY-05009;HLY78;Wnt-C59;Wogonin;NCB-0846;KY-02327;Echinacoside;JW67;IWP-4;Triptonide;Prodigiosin;IWP L6;BML-284 hydrochloride;Astragaloside I;β-catenin-IN-3;NLS-StAx-h;FzM1.8

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