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Ilorasertib hydrochloride
CAS No. : 1847485-91-9
Biological Activity：Ilorasertib (ABT-348) hydrochloride is a potent, orally active and ATP-competitive aurora inhibitor with IC50s of116, 5, 1 nM for aurora A, aurora B, aurora C, respectively. Ilorasertib hydrochloride also is a potent VEGF, PDGF inhibitor. Ilorasertib hydrochloride has the potential for the research of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS)[2].
Research Area：Cancer
Targets：VEGFR|Aurora Kinase|PDGFR
Related Screening Libraries:Covalent Screening Library Plus;Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Epigenetics Compound Library;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Covalent Screening Library;Differentiation Inducing Compound Library;Reprogramming Compound Library;Cytoskeleton Compound Library;Orally Active Compound Library;Anti-Breast Cancer Compound Library;Anti-Lung Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Angiogenesis-Related Compound Library;Targeted Diversity Library;Anti-Liver Cancer Compound Library ;Rare Diseases Drug Library;Anti-Colorectal Cancer Compound Library ;Anti-Pulmonary Fibrosis Compound Library;
Related Small Molecules:(Z)-FeCP-oxindole;DB0614;VEGFR-2-IN-24;BMS-690514;AT9283;PROTAC VEGFR-2 degrader-2;Henatinib;PI3K/VEGFR2-IN-1;Flumatinib mesylate;IHMT-TRK-284;PDGFRα/FLT3-ITD-IN-2;PP58;Hydroxytanshinone IIA;Chiauranib;Foretinib;ZM323881 hydrochloride;Zeteletinib;PTC299;ENMD-2076 Tartrate;Aflibercept;SU5408;Barasertib-HQPA;MAZ51;R1530
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