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CAS No. : 1391712-60-9

Biological Activity:CEP-37440 is a potent, orally active dual FAK/ALK inhibitor with IC50 values of 2.3 nM and 3.5 nM for FAK and ALK, respectively. CEP-37440 decreases the cell proliferation by blocking the autophosphorylation kinase activity of FAK1 (Tyr 397)[2].

Research Area:Cancer

Targets:FAK|Anaplastic lymphoma kinase (ALK)

Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound Library Plus;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Cytoskeleton Compound Library;Orally Active Compound Library;Anti-Breast Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;

Related Small Molecules:ALK-IN-9;Harringtonolide;FAK-IN-8;KRCA-0008;BI-4464;Alectinib-d8;MS4078;TL13-22;NVP-TAE 684;FAK inhibitor 5;ALK5-IN-30;Masitinib;TL13-112;ALK-IN-22;Alectinib;PF-573228;ALK-IN-12;Chloropyramine hydrochloride;FAK inhibitor 6;FAK-IN-6;Entrectinib;Roslin 2 bromide;ALK kinase inhibitor-1;WY-135;PROTAC FAK degrader 1;GSK2256098;TL13-110;ALK inhibitor 1;Envonalkib

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