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Camonsertib

CAS No. : 2417489-10-0

Biological Activity：Camonsertib (RP-3500) is an orally active, selective ATR kinase inhibitor (ATRi) with an IC₅₀ of 1.00 nM in biochemical assays. Camonsertib shows 30-fold selectivity for ATR over mTOR (IC₅₀=120 nM) and >2,000-fold selectivity over ATM, DNA-PK, and PI3Kα kinases. Camonsertib has potent antitumor activity.

Research Area：Cancer

Targets：mTOR|ATM/ATR

Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;

Related Small Molecules:D-α-Hydroxyglutaric acid disodium;ATR-IN-16;ATR-IN-4;Cyclovirobuxine D;WYE-354;L-Leucine-1-13C,15N;CGK733;PI-103-d8;Palomid 529;PI-103 Hydrochloride;Ceralasertib;RMC-5552;OXA-01;L-Leucine-15N;PI3K/mTOR Inhibitor-6;KU 59403;PI3K/mTOR Inhibitor-1;ATM Inhibitor-1;HDACs/mTOR Inhibitor 1;Chromeceptin;hSMG-1 inhibitor 11e;PI3Kα/mTOR-IN-1;ATR-IN-5;ATR inhibitor 1;VE-821;RapaLink-1;Torin 1;Dihydromyricetin;KU-55933

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