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Alvelestat

CAS No. : 848141-11-7

Biological Activity：Alvelestat (AZD9668) is an orally bioavailable, affinity and selective inhibitor of neutrophil elastase (NE) with a pIC₅₀ value of 7.9 nM, a K_i value of 9.4 nM and a K_d value of 9.5 nM.

Research Area：Inflammation/Immunology

Targets：Elastase

Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Metabolism/Protease Compound Library;Clinical Compound Library;Drug Repurposing Compound Library;Anti-diabetic Compound Library;Anti-COVID-19 Compound Library;Pyroptosis Compound Library;Orally Active Compound Library;Targeted Diversity Library;Rare Diseases Drug Library;Human Metabolite Library;

Related Small Molecules:Cyclotheonellazole A;JCP174;BAY-678 racemate;Elastase-IN-1;19α-Hydroxyasiatic acid;Tutuilamide A;MDL 101146;Lodelaben;GW311616 hydrochloride;Elastatinal;DMP 777;BAY-85-8501;FK706;SSR69071;Elastase from porcine pancreas;Secologanoside;Tyrosinase/elastase-IN-1;ZD8321;ZD-0892

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