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VB124
CAS No. : 2230186-18-0
Biological Activity：VB124 is an orally active, potent, and selective MCT4 inhibitor. VB124 can specifically inhibit lactate efflux with IC50s of 8.6 nM and 19 nM for lactate import and export in MDA-MB-231 cells, respectively. VB124 is highly selective for MCT4 over MCT1. VB124 can be used for the research of cardiac hypertrophy, heart failure, and metabolism.
Research Area：Cardiovascular Disease
Targets：Monocarboxylate Transporter
Related Screening Libraries:Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;Anti-Cardiovascular Disease Compound Library;Orally Active Compound Library;Anti-Cancer Metabolism Compound Library;
Related Small Molecules:α-Cyano-4-hydroxycinnamic acid;AR-C141990 hydrochloride;MCT1-IN-2;Silychristin;MSC-4381;AR-C155858;7ACC2;AZD3965;BAY-8002;7ACC1;Syrosingopine
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