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SGC-CBP30
CAS No. : 1613695-14-9
Biological Activity：SGC-CBP30 is a potent and highly selective CBP/p300 bromodomain (Kds of 21 nM and 32 nM for CBP and p300, respectively) inhibitor, displaying 40-fold selectivity over the first bromodomain of BRD4 [BRD4(1)] bound. SGC-CBP30 strongly reduces secretion of IL-17A in Th17 cells and has anti-inflammatory effects[2][3].
Research Area：Cancer|Inflammation/Immunology
Targets：Epigenetic Reader Domain|Histone Acetyltransferase
Related Screening Libraries:Bioactive Compound Library Plus;Epigenetics Compound Library;Immunology/Inflammation Compound Library;Histone Modification Research Compound Library;Anti-Cancer Compound Library;Reprogramming Compound Library;Chemical Probe Library;Anti-Blood Cancer Compound Library;Antidepressant Compound Library;Anti-Pulmonary Fibrosis Compound Library;
Related Small Molecules:RVX-297;BRD4 Inhibitor-19;UNC6349 (Ket2);Curcumin;GSK6853;GSK4028;CBP/p300-IN-19 hydrochloride;NSC 694621;SR-0813;Inobrodib;PCAF-IN-2;Apabetalone;OF-1;I-CBP112;A-485;PLX51107;FKBP12 PROTAC dTAG-7;I-BET151;GSK040;BRM/BRG1 ATP Inhibitor-4;PBRM1-BD2-IN-5;MI-136;IACS-9571;SF2523;L-Moses dihydrochloride;KB02-JQ1;GSK620;INCB-057643
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