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Rapamycin-d3
CAS No. : 392711-19-2
Biological Activity：Rapamycin-d3 (Sirolimus-d3) is the deuterium labeled Rapamycin. Rapamycin is a potent and specific mTOR inhibitor with an IC50of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant[2].
Research Area：Cancer
Targets：FKBP|Autophagy|mTOR
Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Cyclovirobuxine D;dTAGV-1-NEG;WYE-354;SAFit2;L-Leucine-1-13C,15N;PI-103-d8;Palomid 529;FKBP12 PROTAC dTAG-7;PI-103 Hydrochloride;RMC-5552;OXA-01;L-Leucine-15N;PI3K/mTOR Inhibitor-6;dFKBP-1;PI3K/mTOR Inhibitor-1;dTAG-47;PROTAC FKBP Degrader-3;HDACs/mTOR Inhibitor 1;Chromeceptin;hSMG-1 inhibitor 11e;Zapalog;PI3Kα/mTOR-IN-1;RapaLink-1;Torin 1;Dihydromyricetin;SLF TFA
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