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CAS No. : 2206736-04-9

Biological Activity:MRTX-1257 is a selective, irreversible, covalent and orally active KRAS G12C inhibitor, with an IC50 of 900 pM for KRAS dependent ERK phosphorylation in H358 cells.

Research Area:Cancer


Related Screening Libraries:Covalent Screening Library Plus;Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Kinase Inhibitor Library;Anti-Cancer Compound Library;Covalent Screening Library;Ferroptosis Compound Library;Orally Active Compound Library;Glutamine Metabolism Compound Library;Anti-Lung Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Angiogenesis-Related Compound Library;Targeted Diversity Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;

Related Small Molecules:Deltarasin hydrochloride;ZINC09659342;KRAS G12C inhibitor 56;CCG-232601;KRAS G12D inhibitor 14;1A-116;KRAS G12D inhibitor 10;KRAS G12C inhibitor 20;KRAS G12C inhibitor 24;RM-018;KRAS G12C inhibitor 14;APS6-45;6H05;KRpep-2d TFA;KRAS G12C inhibitor 33;KRAS G12C inhibitor 53;K-Ras-IN-1;KRAS G12C inhibitor 41;KRAS G12C inhibitor 26;KRAS G12C inhibitor 16;KRAS inhibitor-11;SOS1-IN-13;BQU57;ZCL278;Digeranyl bisphosphonate;KRAS inhibitor-7;SOS1 activator 1;KRAS inhibitor-14;SAH-SOS1A

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