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CAS No. : 935759-55-0

Biological Activity:MMP13-IN-2 is a potent, selective and orally active MMP-13 inhibitor. MMP13-IN-2 exhibits excellent potency for MMP-13 (IC50=0.036 nM) and selectivities (greater than 1,500-fold) over MMP-1, 3, 7, 8, 9, 14, and TACE. MMP13-IN-2 has the ability to block the release of collagen from cartilage in vitro. MMP13-IN-2 has the potential for collagenase related disease research.

Research Area:Inflammation/Immunology


Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Metabolism/Protease Compound Library;Differentiation Inducing Compound Library;Anti-Pancreatic Cancer Compound Library;Angiogenesis-Related Compound Library;Anti-Pulmonary Fibrosis Compound Library;Coagulation and Anti-coagulation Compound Library;

Related Small Molecules:WAY-170523;CTTHWGFTLC, CYCLIC;Edaravone;D-Isofloridoside;Chondroitin sulfate;Ginsenoside F4;ND-336;Epitheaflagallin 3-O-gallate;Histatin 5 TFA;GW280264X;GI254023X;XL-784 free base;PI3K/AKT-IN-2;Diethyl-pythiDC;FN-439;ONO-4817;Isoliquiritin apioside;Anticancer agent 65;Licoricidin;Astragaloside IV;Phosphoramidon Disodium;Ilomastat;DB04760;Cipemastat;Marimastat;Dnp-PLGLWA-DArg-NH2 TFA;Cynaropicrin;Ro 31-9790

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