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CAS No. : 315702-75-1

Biological Activity:KCC-07 is a potent, selective and brain-penetrant MBD2 (methyl-CpG-binding domain protein 2) inhibitor. KCC-07 prevents binding of MBD2 to methylated DNA and activates brain specific angiogenesis inhibitor 1 (BAI1) inducing anti-proliferative BAI1/p53/p21 signaling. Anticancer activity.

Research Area:Cancer

Targets:DNA Alkylator/Crosslinker

Related Screening Libraries:Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Anti-Cancer Compound Library;CNS-Penetrant Compound Library;Anti-Aging Compound Library;Anti-Lung Cancer Compound Library;Anti-Obesity Compound Library;Transcription Factor-Targeted Library;

Related Small Molecules:Anticancer agent 11;Tesirine;DC10SMe;Duocarmycin TM;Prednimustine;Sibiromycin;Lurbinectedin;Phenylacetic acid mustard;PR-104A;Duocarmycin SA;Duocarmycin DM free base;Imifoplatin;NCI172112;Satraplatin;Trioxsalen;Duocarmycin MA;Miriplatin (hydrate)

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