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Golotimod hydrochloride
Biological Activity:Golotimod hydrochloride (SCV 07 hydrochloride), an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, stimulates thymic and splenic cell proliferation, and improves macrophage function. Golotimod hydrochloride (SCV 07 hydrochloride) inhibits STAT3 signaling and modulates the duration and severity of oral mucositis in animal models that received radiation or a combination of radiation and Cisplatin. Golotimod hydrochloride (SCV 07 hydrochloride) is also a potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2)[2][3].
Research Area:Infection|Inflammation/Immunology|Cancer
Targets:STAT|Bacterial
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Anti-Infection Compound Library;Immunology/Inflammation Compound Library;JAK/STAT Compound Library;Kinase Inhibitor Library;Stem Cell Signaling Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Small Molecule Immuno-Oncology Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Differentiation Inducing Compound Library;Antibacterial Compound Library;Anti-Breast Cancer Compound Library;Anti-Lung Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Obesity Compound Library;Transcription Factor-Targeted Library;Anti-Liver Cancer Compound Library ;Anti-Prostate Cancer Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:Sandramycin;LLO (91-99);Gepotidacin;Oritavancin;Azlocillin sodium salt;Herbimycin A;Antibacterial agent 45;Leucomycin;Isouvaretin;Cirsilineol;Antibacterial agent 99;Nafcillin;Antitubercular agent-28;Ochromycinone;Staurosporine;C188-9;Nucleocidin;(±)-Leucine-13C-1;Ciclopirox-d11;Ciclopirox olamine;Clotrimazole-d5;STAT3-IN-10;SQ109
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