Fasudil Hydrochloride

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Fasudil Hydrochloride

CAS No. : 105628-07-7

Biological Activity:Fasudil (HA-1077; AT877) Hydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively. Fasudil Hydrochloride is also a potent Ca2+ channel antagonist and vasodilator[2][3].

Research Area:Cancer

Targets:ROCK|Autophagy|Calcium Channel|PKC|PKA|HIV

Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Anti-Infection Compound Library;Cell Cycle/DNA Damage Compound Library;Epigenetics Compound Library;Kinase Inhibitor Library;Membrane Transporter/Ion Channel Compound Library;Neuronal Signaling Compound Library;Stem Cell Signaling Compound Library;TGF-beta/Smad Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Antiviral Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Reprogramming Compound Library;Oxygen Sensing Compound Library;Anti-COVID-19 Compound Library;NMPA-Approved Drug Library;Cytoskeleton Compound Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Neuroprotective Compound Library;Rare Diseases Drug Library;Children’s Drug Library;Calcium Channel Blocker Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;Cancer Stem Cells Compound Library;Coagulation and Anti-coagulation Compound Library;

Related Small Molecules:[Ala107]MBP(104-118) TFA;Benidipine hydrochloride;PKI 14-22 amide,myristoylated TFA;CaV1.3 antagonist-1;14-Deoxyandrographolide;BJE6-106;HIV-1 TAT (48-60);Myelin Basic Protein;Seletracetam lithium;Staurosporine;HIV-IN-2;PKC-iota inhibitor 1;Triptonine B;(Rac)-MEM 1003;FC131;Glaucine;Efonidipine hydrochloride monoethanolate;Peritassine A;L-Ascorbic acid sodium salt;Brompheniramine-d6 maleate;Hypericin;MRS 1523

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