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Escin IA
CAS No. : 123748-68-5
Biological Activity：Escin IA is a triterpene saponin isolated from Aesculus hippocastanum, which inhibits HIV-1 protease with IC50 values of 35 μM. Escin IA has anti-TNBC metastasis activity, and its action mechanisms involved inhibition of epithelial-mesenchymal transition process by down-regulating LOXL2 expression[2].
Research Area：Cancer|Infection
Targets：HIV Protease
Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Anti-Infection Compound Library;Metabolism/Protease Compound Library;Natural Product Library;Anti-Cancer Compound Library;Glycoside Compound Library;Medicine Food Homology Compound Library;Terpenoids Library;Traditional Chinese Medicine Active Compound Library;Anti-Cancer Natural Product Library;Plant-Sourced Natural Product Library;
Related Small Molecules:ddCTP trisodium;Cytochalasin A;Pepstatin Ammonium;HIV-1 protease-IN-5;Brecanavir;HIV protease-IN-1;JE-2147;HIV-1 protease-IN-2;Ganodermanondiol;EP39;L-689502;HIV Protease Substrate 1 TFA;HIV-1 protease-IN-6;HIV-1 protease-IN-7;Ganoderic acid B;20(21)-Dehydrolucidenic acid A;TMC310911;Hinokinin;Isoescin IA;DPC-681;CL-197;Rosamultin;SKF107457;PNU-103017
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