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ARCC-4
CAS No. : 1973403-00-7
Biological Activity:ARCC-4 is a low-nanomolar Androgen Receptor (AR) degrader based on PROTAC, with a DC50 of 5 nM. ARCC-4 is an enzalutamide-based von Hippel-Lindau (VHL)-recruiting AR PROTAC and outperforms enzalutamide. ARCC-4 effectively degrades clinically relevant AR mutants associated with antiandrogen therapy.
Research Area:Cancer
Targets:Androgen Receptor|PROTACs
Related Screening Libraries:Bioactive Compound Library Plus;Anti-Cancer Compound Library;Chemical Probe Library;Transcription Factor-Targeted Library;Anti-Prostate Cancer Compound Library;Nuclear Receptor Compound Library;
Related Small Molecules:PROTAC Sirt2 Degrader-1;DB0614;VPC-14449;PROTAC VEGFR-2 degrader-2;dTAGV-1-NEG;CCT367766 formic;AC-262536;HDAC6 degrader-1;PROTAC Axl Degrader 2;PhosTAC7;MS98;JPS014;PROTAC PARP1 degrader;MD-224;FKBP12 PROTAC dTAG-7;GTx-007;SJ10542;MS8815;RIP2 Kinase Inhibitor 4;PROTAC EGFR degrader 7;SJ995973;Linuron-d6;CC-885-CH2-PEG1-NH-CH3;MI-136;dFKBP-1;MI-389;BSJ-4-116;MS4078
Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
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