For research use only. We do not sell to patients.
ANI-7
CAS No. : 931417-26-4
Biological Activity：ANI-7 is an activator of aryl hydrocarbon receptor (AhR) pathway. ANI-7 inhibits the growth of multiple cancer cells, and potently and selectively inhibits the growth of MCF-7 breast cancer cells with a GI50 of 0.56 μM. ANI-7 induces CYP1-metabolizing mono-oxygenases by activating AhR pathway, and also induces DNA damage, checkpoint Kinase 2 (Chk2) activation, S-phase cell cycle arrest, and cell death in sensitive breast cancer cell lines[2][3].
Research Area：Cancer
Targets：Aryl Hydrocarbon Receptor|Checkpoint Kinase (Chk)
Related Screening Libraries:Covalent Screening Library Plus;Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Covalent Screening Library;Anti-Breast Cancer Compound Library;Transcription Factor-Targeted Library;
Related Small Molecules:VER-00158411;FICZ;MeBIO;AhR agonist 2;BML-277;CHK1-IN-3;Indole-3-pyruvic acid;GDC-0425;Benzyl butyl phthalate;L-Kynurenine-d4-1;Pifithrin-α hydrobromide;PF 477736;SCH900776;SAR-020106;Prexasertib;CHK1-IN-2;Skatole;ITE;L-Kynurenine sulfate;DiMNF;Chk1-IN-6;AHR antagonist 2;Skatole-d3;D-Kynurenine;Monalizumab
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
About Us:
- MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use；
- Structurally and synthetically diverse biologically active compounds；
- roduct quality is the key to our success and we take pride in offering only the highest-grade products.；
- We provide HNMR, LC-MS, HPLC, stability testing and activity assays of our products to clients.；
- Product identity, quality, purity and activity are assured by our robust quality control programs and procedures.；
- Customized order volume ranging from milligrams to kilograms scale；
Structurally and synthetically diverse biologically active compounds；
We provide customer-oriented services. To explore more, please contact us at [email protected]. Our team will gladly assist you.
