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5-Fluorouracil
CAS No. : 51-21-8
Biological Activity：5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer[2]. 5-Fluorouracil also inhibits HIV[3].
Research Area：Cancer
Targets：Nucleoside Antimetabolite/Analog|HIV|Endogenous Metabolite|Apoptosis
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Anti-Infection Compound Library;Apoptosis Compound Library;Cell Cycle/DNA Damage Compound Library;Metabolism/Protease Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Antiviral Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Reprogramming Compound Library;Nucleotide Compound Library;NMPA-Approved Drug Library;FDA Approved & Pharmacopeial Drug Library;Anti-Breast Cancer Compound Library;Anti-Lung Cancer Compound Library;Drug-Induced Liver Injury (DILI) Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Tumorigenesis-Related Compound Library;Children’s Drug Library;Chemotherapy Drug Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;Anti-Prostate Cancer Compound Library;
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